JTHO May 2025

Kim et al examined data from Korea’s National Health Information Database and 11 academic hospital screening centres and found widespread guideline-discordant low dose CT screening correlates with lung cancer overdiagnosis and increased healthcare utilization, particularly in women. Which of the following is NOT true about screening implementation:

Screening should prioritize reducing mortality over increasing detection rates, by targeting individuals at risk of lethal lung cancer who would benefit from early intervention.
Randomized controlled trials should assess the mortality benefits and potential overdiagnosis of screening populations outside current eligibility standards, such as those with minimal smoking exposure
Lung nodule growth assessment and risk prediction models should be used in clinical practice to ensure invasive procedures are reserved for cases in which growth affects prognosis.
Growth thresholds have been established to guide optimal interventions for subsolid