HRCR April 2025 Quiz

Editorial note: The following quiz is related to the article How to Approach Multiple Arrhythmias in a Young Athlete with SCN5A Mutation Andreas Müssigbrodt and colleagues in the April 2025 issue of Heart Rhythm Case Reports.

1. Which of the following condition(s) is/are not associated with SCN5A mutations?

A. Brugada syndrome and Long QT syndrome type 3
B. Atrial fibrillation, atrial flutter, atrial standstill, sick sinus syndrome, progressive cardiac conduction disease
C. Hypertrophic cardiomyopathy
D. Arrhythmogenic and dilated cardiomyopathy

2. In young patients with atrial flutter or atrial fibrillation without common risk factors, what should be considered?

A. Immediate catheter ablation
B. Long-term anticoagulation only
C. Genetic testing
D. Permanent pacemaker implantation

3. Which of the following symptoms could indicate ICD implantation in a patient with an SCN5A mutation, even without documented ventricular tachyarrhythmias?

A. Syncope, overlap syndrome, and progressive cardiac conduction disease
B. Asymptomatic atrial fibrillation
C. No symptoms but a family history of heart failure
D. Normal conduction and no syncope

4. What was a primary consideration for the patient’s decision to continue playing soccer?

ICD implantation automatically permits all sports activities
The patient experienced no further arrhythmic events after ablation
The shared decision-making process between the athlete and physician, guided by current recommendations
Competitive sports participation is restricted for all ICD patients